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The show premiered on October 2, 2001 and focuses on the professional and personal lives of several characters working at Sacred Heart, a fictional hospital in an unspecified city. Its use of narration, unusually verbose characters, abrupt segues between subplots, breakneck pace and scenes of surreal escapism (usually presented as the thoughts and reveries of the main characters), counterpointed by poignant scenes where the characters address how doctors deal with death and issues in their personal lives distinguishes it from other series.
It also lacks a laugh track, a traditional device in most sitcoms. Also, unlike most sitcoms, it uses a single camera setup (as opposed to a multicamera setup). The show is structured around various storylines, which are thematically linked via voice-overs, intended to deliver a small life-lesson, and often a joke. The series is also notable for numerous cameo appearances by well-known actors.
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